Welcome to MCADDI

About MCADDI 2019

Biocon Academy, in association with American Chemical Society (ACS) Medicinal Chemistry Division and Pharma Innovation Sourcing Centre LLC USA, proudly announce Medicinal Chemistry, Drug Discovery & Development India 2019 (MCADDI 2019), a residential course in medicinal chemistry and drug discovery and Development to be held on March, 2019 at the Biocon Academy Campus in Bangalore, India. This five days program will be co-sponsored by the American Chemical Society Division of Medicinal Chemistry and the International Union of Pure and Applied Chemistry (IUPAC). MCADDI 2019 builds on the successful Medicinal Chemistry and Drug Discovery & Development India 2017 (MCADDI 2017) course, which was held at Biocon Academy on February of 2017, and drew over 100 attendees from industry and academia.

MCADDI 2019 will present the principles of Medicinal Chemistry, Drug Discovery & Development in a format that is designed for industrial and academic participants who are currently working in this area, or plan to do so. The course will include twenty-eight lectures on target identification and validation, lead optimization, drug metabolism and pharmacokinetics, molecular modelling, bioisosteres, structure based drug design, drug-like properties, pharmaceutics, discovery of biologics and other topics of interest to drug discovery & development scientists. In MCADDI 2019, we have dedicated several lectures on pharmaceutical development CMC topics including process optimization and development, bio-pharmaceutics and analytical sciences as well as integrated drug discovery and development case histories. The sessions are designed to be highly interactive, and will include case studies to enhance the learning process. The highlight of this program would be the inclusion of pharmaceutical development with the discovery value chain.


From the afternoon of 4th March to 9th March - 2019 (5 days).


Medicinal Chemistry, Drug Discovery & Development India 2019 (MCADDI 2019)

Hall- Neville Bain, 4th Floor, Biocon House,

Semicon Park, Electronics City Phase II,

Bangalore 560100

MCADDI 2019 Program Outline

  1. Basic Principles of Medicinal Chemistry
  2. Target Identification and Validation
  3. Hit Identification: High-Throughput / Phenotypic/Virtual / Fragment screening
  4. Designing Around Toxicophores in Drug Discovery 
  5. Special Topic: Applications of Fluorine in Drug Design and Discovery
  6. Enzymes, Receptors and Ion Channels  
  7. Tactical Applications of Bioisosteres in Drug Design
  8. Applications of Heterocycles in Drug Design
  9. Hit-to-Lead Process
  10. Lead Optimization
  11. Plasma Protein Binding
  12. Drug Metabolism and PK
  13. Basics and Application of Structure Based Design –Molecular Modelling and Fragment based in Drug Discovery
  14. Saroglitazar (Lipaglyn®) for Treatment of Dyslipidemia and Hypertriglyceridemia in Type II Diabetes
  15. G-Protein Coupled Receptors
  16. Ruxolitinib (Jakafi®) for Treatment of Polycythemia Vera and Myelofibrosis 
  17. Introduction to Biologics
  18. Biologics and Biosimilar Design and Development  
  19. Antibody-Drug Conjugates (ADCs)
  20. Topic TBD
  21. General introduction to Process Chemistry; Phase-appropriate process development
  22. Basic Principles Bio pharmaceutics & Analytical Sciences
  23. Case History of Integrated Drug Discovery and Process Development:  HIV-1 Attachment Inhibitors - Part 1
  24. Case History of Integrated Drug Discovery and Process Development:  HIV-1 Attachment Inhibitors - Part 2
  25. Drug Product Development - HIV-1 Attachment Inhibitors and other Case Studies
  26. Current Trends in Indian - Pharmaceutical and Biotechnology Industry
  27. Future Trends in Drug Discovery
  28. Perspectives on Pharmaceutical Development
  29. Integrated Case History - Process Development 
  30. Case History of Integrated Drug Discovery and Process Development: Part 2
  31. Case History of Integrated Drug Discovery and Process Development: Part 3

As the world’s largest scientific society, the American Chemical Society serves over 156,000 members in over 140 countries. ACS is happy to offer MCADDI 2019 registrants a complimentary one year membership to nonmembers. Once your conference registration is completed, please click here to redeem your complimentary membership in ACS and the ACS Technical Division of your choice.

Corporate Film:Biocon Academy,a Center of Excellence for Advanced learning in Applied Biosciences.
Biocon Academy
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Advisory Board
Dr. Balu N. Balasubramanian
Pharma Innovation Sourcing Center, LLC
Dr. William Greenlee
Med Chem Discovery Consulting, LLC
M.B Chinappa
Organizing Committee
Dr. Venkat Palle
Lupin Pharma
Dr. Sudhir Kumar Singh
GVK Biosciences
Dr. Arvind Mathur
Dr. Manjunath Rama Rao
BBRC, India
Ms. Bindu Ajit
Biocon Academy
S.S. Eswaran
Biocon Academy